Journal Club February
Interesting publications came out again this month. One is attached – it was not published this month, but is very interesting in itself and was sent to me by the author on request as we do not otherwise have full-text access to it: Lagrand 2023 – Cold plasma treatment is safe for diabetic foot ulcers and decreases Staphylococcus aureus bacterial load
But there is also news:
- First, of course, my favorite: Do you remember Paul the hedgehog? There is now a whole study (from Bonn, of course) with CAP in hedgehogs. Non-invasive physical plasma improves conventional wound management of cut and bite wounds in wild European hedgehogs. https://pubmed.ncbi.nlm.nih.gov/39837903/
This wildlife clinical trial demonstrates that NIPP can be used to improve wound healing in wild European hedgehogs. It is conceivable that NIPP therapy could also lead to positive effects in other injured wild animals, domestic animals or livestock.
Really well done study, nice summary of the data situation for animals in general, good results – can also be shown well on social media etc. in my opinion.
- https://pubmed.ncbi.nlm.nih.gov/39796119/ Cellular Response of Immune Cells in the Upper Respiratory Tract After Treatment with Cold Atmospheric Plasma In Vitro
Also with plasma care or “intensive care” and “infection care”: Preclinical publication on the “fog plasma” project and the safety of its application to lung cells from Regensburg.
- Effect of cold atmospheric plasma on common oral pathogenic microorganisms: a narrative review https://pmc.ncbi.nlm.nih.gov/articles/PMC11774187/
A review of the data on CAP on “common oral pathogenic microorganisms”: Numerous articles have shown that CAP has a potent antimicrobial effect against common oral pathogens, including bacteria, fungi, and viruses, primarily due to the synergy of various factors, especially reactive oxygen and nitrogen species.
Always good for arguments in this direction.
- Enhanced Cytotoxic Effects of Cold Plasma Deposition of Topotecan: A Novel Approach for Local Cancer Drug Delivery to Glioblastoma Cells
https://pubmed.ncbi.nlm.nih.gov/39857983/
Interesting because it investigates both the negative effect of plasma on cancer cells and the synergistic effect between plasma and drugs. These results revealed a pathway for new combinations and approaches to local drug application for a range of cancers.
- https://pmc.ncbi.nlm.nih.gov/articles/PMC11739377/ Subcytotoxic transepidermal delivery using low intensity cold atmospheric plasma
Perhaps interesting with regard to safety studies of other plasma devices and the combination of plasma and active ingredient uptake – I am not familiar with the device itself.
