Journal Club January

There were also a few new publications in December that are worth a look:

  1. https://pubmed.ncbi.nlm.nih.gov/39673112/ Efficacy of Cold Atmospheric Plasma in Chronic Diabetic Foot Ulcer Management: A Case Report
    The case report by Thomas Serena from the Serena Research Group in the USA on plasma care is a first, small step for us towards establishing it in the USA. Perhaps it is also worth a mention on the homepage? It is a very successful case report, but the essential thing is the implementation in the USA.
    Excerpt from the abstract: CASE REPORT A 69-year-old man with a chronic non-healing diabetic foot ulcer on the plantar surface of his left foot underwent multiple failed treatments over 60 weeks, including traditional wound care and advanced clinical trials, before being treated with CAP, leading to significant wound closure over the course of 15 weeks. CONCLUSIONS This report has highlighted the challenges of managing chronic diabetic foot ulcers and has shown that CAP can promote wound healing.
  2. https://pubmed.ncbi.nlm.nih.gov/39197495/ A randomized controlled trial analyzing nonthermal atmospheric plasma for the treatment of verruca vulgaris in pediatric patients
    An interesting paper from two points of view. On the one hand, the indication verruca vulgaris is very interesting from a dermatological point of view. Secondly, children with an average age of 9.5 years were treated, which is good for our arguments from a safety point of view. Unfortunately, I don’t have full text access, so I can’t see which CAP device was used. Also, the effects are not significant, but nevertheless the safety of the application was confirmed.
  3. https://pmc.ncbi.nlm.nih.gov/articles/PMC11650461/ Disinfection of dental root canals by cold atmospheric plasma: a systematic review and meta-analysis of dental biofilm
    Quite a detailed review on biofilms, especially in the dental field. Can be used as a good starting point for questions in this direction.
  4. https://pubmed.ncbi.nlm.nih.gov/39650231/ Antitumor effects of plasma-activated solution on a murine melanoma model in vivo and in vitro
    Mouse model paper, but very interesting, as it shows the anti-tumor effects of CAP-activated solution and again supports the safety of the application, and thus again points to the selectivity of CAP.
  5. https://pmc.ncbi.nlm.nih.gov/articles/PMC11640168/ The Potential of a Novel Cold Atmospheric Plasma Jet as a Feasible Therapeutic Strategy for Gingivitis-A Cell-Based Study
    Very nice in vitro paper on the safety and effectiveness of the application in gingivitis, i.e. in the dental field. It is also exciting because it supports the safety of CAP on mucous membranes (and has very nice cell staining images).

Best regards and have fun looking through 🙂

Lisa